Monday, 26 May 2014

Nitrite skin bacteria gemma

 http://www.nytimes.com/2014/05/25/magazine/my-no-soap-no-shampoo-bacteria-rich-hygiene-experiment.html?smid=pl-share
my-no-soap-no-shampoo-bacteria-rich-hygiene-experiment. 


Gemma says:
There was perhaps too much nitrogen in my original comment, so here goes some science to de-confuse the dear reader (on the interplay of sun, nitrogen, ammonia-oxidizing bacteria and CVD health):
Is sunlight good for our heart?
“We propose here that many of the beneficial effects of sunlight, particularly those related to cardiovascular health, are mediated by mechanisms that are independent of melatonin, vitamin D, and exposure to UVB alone. Specifically, we suggest that the skin is a significant store of nitric oxide (NO)-related species that can be mobilized by sunlight and delivered to the systemic circulation to exert coronary vasodilator and cardioprotective as well as antihypertensive effects (Figure 1). We further hypothesize that this dermal NO reservoir is a product of local production and dietary supply with nitrate-rich foods.
[...]
A recent human study has demonstrated that UVA irradiation can increase plasma nitrite levels by 40%. This is intriguing considering that in animal models, a similar increase in nitrite is associated with cardioprotection following I/R injury. Dietary nitrate intake (predominantly from green leafy vegetables) may provide an alternative source of nitrite.”
http://eurheartj.oxfordjournals.org/content/early/2010/03/09/eurheartj.ehq069.full

 Gemma says:
And now on the importance of the ammonia oxidising bacteria (AOB) living on the skin:
Soil bacteria, nitrite and the skin
“Mammals likely evolved with AOB on their skin, providing their host with nitrite by conversion of ammonia in providing their host with nitrite by conversion of ammonia in sweat with scalp, pubic and underarm hair providing a suitable niche due to enhanced sweat production, increased warmth, increased relative humidity and protection of light (the latter is important as ammonia monooxygenase activity is inhibited by light). Low NO increases androgen levels which increase growth of pubic hair, expanding the AOB niche thereby increasing NO/NOx production and absorption in a feedback loop.
The production of a suitable niche for these bacteria provides a rationale for non-thermal sweating (e.g., under stress) (to supply NO/nitrites, the location of body hair (near lymph nodes), why the skin of the scalp is thin and well vascularized (to enhance NO/nitrite absorption), any why the sweat glands are most abundant on the feet and palms (fro antimicrobial effects of acidified nitrite in surfaces in contact with soil).
http://www.researchgate.net/publication/227124248_Soil_bacteria_nitrite_and_the_skin
(full text available)

Sunday, 18 May 2014

Grace Conversations

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  1. GI stool 2200
  2. Mitoq10 intro
  3. Cambridge digestion of starch
  4. Dalton Hamstring Strech
  5. Organic straved beetroot have better anti cancer effect
  6. Amla for dog pancreatitis
  7. Salicin for skin and gut
  8. DHL for 23and me
  9. Arab plant circadian cycle salicin midnight
  10. Polly matzinger forum cnacer
  11. bolon cancer relapse
  12. Banana mitogen
  13. Grace slide show UK colon cancer
  14. CAPP aspirin
  15. Boots No 7’s new Protect & Perfect Advanced Serum,
  16. Shao Ping sour dough
  17. Browning white fat cells
  18. Pot Citrate Beetroot powder melbourne
  19. Beetroot Bread
  20. Fusobacterium colon cancer dental
  21. Ultrasound cheap for blood flow to brain ebay 160$
  22. GDF11
  23. thesis gene-scfa-fat
  24. broccli helps colitis DSS attack
  25. Thiamin lonsdale 


1 to 20 of 22

Selected: 11
1.
Paterson JR, Srivastava R, Baxter GJ, Graham AB, Lawrence JR.
J Agric Food Chem. 2006 Apr 19;54(8):2891-6.
PMID:
16608205
[PubMed - indexed for MEDLINE]
2.
Baxter GJ, Graham AB, Lawrence JR, Wiles D, Paterson JR.
Eur J Nutr. 2001 Dec;40(6):289-92.
PMID:
11876493
[PubMed - indexed for MEDLINE]
3.
Baxter GJ, Lawrence JR, Graham AB, Wiles D, Paterson JR.
Ann Clin Biochem. 2002 Jan;39(Pt 1):50-5.
PMID:
11853189
[PubMed - indexed for MEDLINE]
4.
Lawrence JR, Peter R, Baxter GJ, Robson J, Graham AB, Paterson JR.
J Clin Pathol. 2003 Sep;56(9):651-3.
PMID:
12944546
[PubMed - indexed for MEDLINE]
Free PMC Article
5.
Duthie GG, Kyle JA, Jenkinson AM, Duthie SJ, Baxter GJ, Paterson JR.
J Agric Food Chem. 2005 Apr 20;53(8):2897-900.
PMID:
15826036
[PubMed - indexed for MEDLINE]
6.
Paterson J, Baxter G, Lawrence J, Duthie G.
Proc Nutr Soc. 2006 Feb;65(1):93-6. Review.
PMID:
16441948
[PubMed - indexed for MEDLINE]
7.
McCreadie RG, Kelly C, Connolly M, Williams S, Baxter G, Lean M, Paterson JR.
Br J Psychiatry. 2005 Oct;187:346-51.
PMID:
16199794
[PubMed - indexed for MEDLINE]
Free Article
8.
Paterson SG, Robson JE, McMahon MJ, Baxter G, Murphy MJ, Paterson JR.
Ann Clin Biochem. 2006 Sep;43(Pt 5):369-71.
PMID:
17022878
[PubMed - indexed for MEDLINE]
9.
Wood A, Baxter G, Thies F, Kyle J, Duthie G.
Mol Nutr Food Res. 2011 May;55 Suppl 1:S7-S14. doi: 10.1002/mnfr.201000408. Epub 2011 Feb 23. Review.
PMID:
21351247
[PubMed - indexed for MEDLINE]
10.
Mitra A, Hannay D, Kapur A, Baxter G.
Prim Health Care Res Dev. 2011 Oct;12(4):329-34. doi: 10.1017/S1463423611000193.
PMID:
22284947
[PubMed - indexed for MEDLINE]
11.
Shaukat A, Grau MV, Church TR, Baxter G, Barry EL, Summers R, Sandler RS, Baron JA.
Cancer Epidemiol Biomarkers Prev. 2011 Apr;20(4):679-82. doi: 10.1158/1055-9965.EPI-10-1135. Epub 2011 Feb 9.
PMID:
21307305
[PubMed - indexed for MEDLINE]
Free PMC Article