http://www.huffingtonpost.co.uk/mark-s-whiteley/varicose-veins-discovery_b_3855320.html
Wednesday, 30 April 2014
Tuesday, 29 April 2014
Seth Died post Easter 2014
Seth died last Sunday April 27th 2014.
This is one of the best posts in his blog from an ordinary citizen scientist
I believe, due to experiences I will expand upon below, that excess sulfur compounds, especially sulfites, may contribute to and even cause irritable bowel syndrome (IBS). If you have IBS, you can try to verify this in a few ways.
1) Try molybdenum. I take Carlson Lab’s Moly-B 500 mcg tablets (one tablet/day).
2) Avoid foods and supplements high in sulfur.
3) If you have already purchased the services of 23&me or want to, you can look at this thread in the forums — “Reactions to food containing sulfites, sulfur dioxide, bisulfite, metabisulfite. SUOX gene” — and see if you have the same polymorphisms, though if you just do the first two, you’ll be able to guess.
The woman who started that thread at 23&me goes by the name Red Ringlets. She asked if anyone with four polymorphisms involved in sulfur processing experience reactions to sulfur compounds commonly added to foods as preservatives and/or for antibacterial purposes. I have three of these polymorphisms. I knew I was allergic to certain medicines, but I had not thought about the effect of sulfur coming from my food and supplements largely because I associated reactions to sulfur with hives and headaches.
Several years ago once the appetite suppression the Shangri-La diet kicked in, I adopted what most would consider a paleo template for my diet. This means I generally avoid grains, legumes, and dairy with caveats (like rice, now that I work out, and butter because it is animal fat and therefore good according to evolutionary thinking). Additionally a substantial amount of the meat that I buy comes from conventional sources.
Despite not being technically paleo, I enjoyed coffee, chocolate, and red wine, which are all high in sulfur. Sulfur is also added to various coconut products, shrimp, fish, dried fruit — many products a person trying to eat paleo might eat. I ate them. And I would have gastrointestinal distress that I could not explain despite getting leaner.
In the summer of 2013 after a few social functions that served grilled hamburgers, grilled shrimp, and other summer party foods a paleo dieter might think would be okay, I went to the emergency room. I had a serious pain where my appendix should be. Sometimes the pain would get worse after eating, and I would often get diarrhea. I thought I had appendicitis, but the doctors found nothing wrong. They took regular X-rays and did blood tests, and came back and said they found nothing. I got really angry about that, so they ordered a CT scan. The CT scan also showed nothing. They told me I had IBS because they had gone through a list of other things it might be and eliminated all of them.
When I went to the emergency room, I also inadvertently took with me a large amount of sulfur. I had a couple of 90% Lindt bars with me. My chocolate intake had risen during that time, too. I had stuff to do, places to go — and an excuse to treat chocolate like a food group.
I was aware, from reading on the internet, of FODMAPs, which are osmotic carbohydrates that draw water into the gut, causing gas, bloating, cramping and diarrhea. They seemed a likely culprit because these were the symptoms I experienced. Following a low FODMAP diet seemed to help, but not perfectly so.
There is some overlap between the two lists of foods to avoid (high sulfur and high FODMAP), so avoiding FODMAPs might have helped because it made me avoid sulfur. It also made it possible for me to have days where I didn’t eat any FODMAP foods but I would eat something like shrimp and then I’d have symptoms despite not eating any FODMAPs. So, looking back on it, I think of attending a wedding, eating nothing but shrimp, and drinking a little bit of red wine, and then having IBS problems and not understanding why because it doesn’t fit in well with the FODMAP story. I think FODMAPs are problematic in a gut that has already been compromised, but FODMAPs are not evolutionarily novel, and thus are unlikely to be the original cause of the problem.
Since it was summer and I just gotten through that ER experience, I stopped eating a lot of fruits, chocolate, wine, etc. One of the things that figures largely for me as a source of sulfur during this time though is shrimp. I kept thinking it was a safe food to eat, and didn’t realize until later it was a source of sulfur. Additionally, I was taking several supplements that contained sulfur: gelatin, biotin, glutathione, NAC, ALA, MSM. I had gotten into the habit of trying different supplements since 2010 because of a neuralgia that neither doctors nor dentists could explain. Though I was not taking all of them at once, I did supplement enough to assume I kept my sulfur level high throughout this time period.
I noticed the thread Red Ringlets posted at 23&me in August of 2013. In October I asked whether or not sulfur could cause a dehydrating effect. I asked this because I’ve noticed wine can take more water out of me than other drinks containing alcohol do. I didn’t get an answer to that question, but I began to explore some of the links people had put into the thread. I read through this site: www.learningtarget.com. I found the following page particularly helpful because it mentioned that molybdenum is a vital part of the sulfite oxidase enzyme: Vitamins and Supplements for Sulfite Problems.
I still had not made a connection between sulfur and irritable bowel syndrome, but I decided to supplement with fucoidan, which is a sulfated polysaccharide found in some seaweeds. I thought it would help my gut, but it caused diarrhea. It was as if I had decided to supplement with cholera. The effect was large and obvious enough for me to realize it was probably the supplement I had just taken. Once I accepted that, I put together what I had learned from the 23&me thread.
Now, in retrospect, I think fucoidan may have caused diarrhea for completely different reasons. I learned in my 23&me health report that I am norovirus resistant, and I have subsequently read that this has something to do with my ability (or inability) to make fucose. I can’t remember where I read this, but it made me think fucoidan could have destabilized my gut flora for reasons unrelated to its sulfur content.
Whatever the reason for the extreme reaction to fucoidan, I decided the beneficial reaction to molybdenum meant that I had a genetically limited capacity to deal with all the extra sulfur in my food and supplements. I threw out my high sulfur supplements and tried to stick to low sulfur foods. Within about two weeks I started having normal bowel movements. This was better than what I was achieving before the entire fucoidan fiasco. I had migrated to a diet of rice and fish which helped me approximate normalcy, but any time I tried to have any variety in my diet, I would run into problems. By avoiding sulfur, I was able to eat a larger variety of foods without incident.
Eventually I found if I was very careful, I could eat small amounts of high sulfur foods, but this is hit or miss because I can’t reliably gauge what the potential dose is, nor is it always clear whether a food has sulfur in it. I still supplement with molybdenum but I think the long term strategy here is both molybdenum and at least avoiding high sulfite foods because my genetics suggest it is doubtful I am going to be able to process as many sulfites as other people do regardless of how much molybdenum I have.
As I mentioned before, I think once the gut is compromised, many things become irritants. Removing excess sulfur has increased my health a lot, but I suspect I need to improve gut flora, and possibly heal some tissue damage. The doctors may not be able to see it, but I still have residual pain in the region where my appendix is.
This is one of the best posts in his blog from an ordinary citizen scientist
Journal of Personal Science: Molybdenum and Avoiding Sulfur Helped My IBS
by August Hurtel
I live in Shreveport, Louisiana and work in the interlibrary loans department at Shreve Memorial library. I am 39 years old.I believe, due to experiences I will expand upon below, that excess sulfur compounds, especially sulfites, may contribute to and even cause irritable bowel syndrome (IBS). If you have IBS, you can try to verify this in a few ways.
1) Try molybdenum. I take Carlson Lab’s Moly-B 500 mcg tablets (one tablet/day).
2) Avoid foods and supplements high in sulfur.
3) If you have already purchased the services of 23&me or want to, you can look at this thread in the forums — “Reactions to food containing sulfites, sulfur dioxide, bisulfite, metabisulfite. SUOX gene” — and see if you have the same polymorphisms, though if you just do the first two, you’ll be able to guess.
The woman who started that thread at 23&me goes by the name Red Ringlets. She asked if anyone with four polymorphisms involved in sulfur processing experience reactions to sulfur compounds commonly added to foods as preservatives and/or for antibacterial purposes. I have three of these polymorphisms. I knew I was allergic to certain medicines, but I had not thought about the effect of sulfur coming from my food and supplements largely because I associated reactions to sulfur with hives and headaches.
Several years ago once the appetite suppression the Shangri-La diet kicked in, I adopted what most would consider a paleo template for my diet. This means I generally avoid grains, legumes, and dairy with caveats (like rice, now that I work out, and butter because it is animal fat and therefore good according to evolutionary thinking). Additionally a substantial amount of the meat that I buy comes from conventional sources.
Despite not being technically paleo, I enjoyed coffee, chocolate, and red wine, which are all high in sulfur. Sulfur is also added to various coconut products, shrimp, fish, dried fruit — many products a person trying to eat paleo might eat. I ate them. And I would have gastrointestinal distress that I could not explain despite getting leaner.
In the summer of 2013 after a few social functions that served grilled hamburgers, grilled shrimp, and other summer party foods a paleo dieter might think would be okay, I went to the emergency room. I had a serious pain where my appendix should be. Sometimes the pain would get worse after eating, and I would often get diarrhea. I thought I had appendicitis, but the doctors found nothing wrong. They took regular X-rays and did blood tests, and came back and said they found nothing. I got really angry about that, so they ordered a CT scan. The CT scan also showed nothing. They told me I had IBS because they had gone through a list of other things it might be and eliminated all of them.
When I went to the emergency room, I also inadvertently took with me a large amount of sulfur. I had a couple of 90% Lindt bars with me. My chocolate intake had risen during that time, too. I had stuff to do, places to go — and an excuse to treat chocolate like a food group.
I was aware, from reading on the internet, of FODMAPs, which are osmotic carbohydrates that draw water into the gut, causing gas, bloating, cramping and diarrhea. They seemed a likely culprit because these were the symptoms I experienced. Following a low FODMAP diet seemed to help, but not perfectly so.
There is some overlap between the two lists of foods to avoid (high sulfur and high FODMAP), so avoiding FODMAPs might have helped because it made me avoid sulfur. It also made it possible for me to have days where I didn’t eat any FODMAP foods but I would eat something like shrimp and then I’d have symptoms despite not eating any FODMAPs. So, looking back on it, I think of attending a wedding, eating nothing but shrimp, and drinking a little bit of red wine, and then having IBS problems and not understanding why because it doesn’t fit in well with the FODMAP story. I think FODMAPs are problematic in a gut that has already been compromised, but FODMAPs are not evolutionarily novel, and thus are unlikely to be the original cause of the problem.
Since it was summer and I just gotten through that ER experience, I stopped eating a lot of fruits, chocolate, wine, etc. One of the things that figures largely for me as a source of sulfur during this time though is shrimp. I kept thinking it was a safe food to eat, and didn’t realize until later it was a source of sulfur. Additionally, I was taking several supplements that contained sulfur: gelatin, biotin, glutathione, NAC, ALA, MSM. I had gotten into the habit of trying different supplements since 2010 because of a neuralgia that neither doctors nor dentists could explain. Though I was not taking all of them at once, I did supplement enough to assume I kept my sulfur level high throughout this time period.
I noticed the thread Red Ringlets posted at 23&me in August of 2013. In October I asked whether or not sulfur could cause a dehydrating effect. I asked this because I’ve noticed wine can take more water out of me than other drinks containing alcohol do. I didn’t get an answer to that question, but I began to explore some of the links people had put into the thread. I read through this site: www.learningtarget.com. I found the following page particularly helpful because it mentioned that molybdenum is a vital part of the sulfite oxidase enzyme: Vitamins and Supplements for Sulfite Problems.
I still had not made a connection between sulfur and irritable bowel syndrome, but I decided to supplement with fucoidan, which is a sulfated polysaccharide found in some seaweeds. I thought it would help my gut, but it caused diarrhea. It was as if I had decided to supplement with cholera. The effect was large and obvious enough for me to realize it was probably the supplement I had just taken. Once I accepted that, I put together what I had learned from the 23&me thread.
Now, in retrospect, I think fucoidan may have caused diarrhea for completely different reasons. I learned in my 23&me health report that I am norovirus resistant, and I have subsequently read that this has something to do with my ability (or inability) to make fucose. I can’t remember where I read this, but it made me think fucoidan could have destabilized my gut flora for reasons unrelated to its sulfur content.
Whatever the reason for the extreme reaction to fucoidan, I decided the beneficial reaction to molybdenum meant that I had a genetically limited capacity to deal with all the extra sulfur in my food and supplements. I threw out my high sulfur supplements and tried to stick to low sulfur foods. Within about two weeks I started having normal bowel movements. This was better than what I was achieving before the entire fucoidan fiasco. I had migrated to a diet of rice and fish which helped me approximate normalcy, but any time I tried to have any variety in my diet, I would run into problems. By avoiding sulfur, I was able to eat a larger variety of foods without incident.
Eventually I found if I was very careful, I could eat small amounts of high sulfur foods, but this is hit or miss because I can’t reliably gauge what the potential dose is, nor is it always clear whether a food has sulfur in it. I still supplement with molybdenum but I think the long term strategy here is both molybdenum and at least avoiding high sulfite foods because my genetics suggest it is doubtful I am going to be able to process as many sulfites as other people do regardless of how much molybdenum I have.
As I mentioned before, I think once the gut is compromised, many things become irritants. Removing excess sulfur has increased my health a lot, but I suspect I need to improve gut flora, and possibly heal some tissue damage. The doctors may not be able to see it, but I still have residual pain in the region where my appendix is.
10 Responses to “Journal of Personal Science: Molybdenum and Avoiding Sulfur Helped My IBS”
Friday, 25 April 2014
Lynch Sydrome and Aspirin
- the cancer incidence statistics for Sri Lanka show that the lowest number is for Muslim females, while Muslim males have rectal cancer. So find out what Muslim sri Lanka females eat.
- April 2014 advance: researchers found that individuals whose colons have high levels of a specific gene product - 15-hydroxyprostaglandin dehydrogenase (15-PGDH) RNA - dramatically reduce their chances of developing colorectal cancer by taking aspirin. In contrast, the analgesic provides no benefit to individuals whose colons show low levels of 15-PGDH
- Eat Lesion rich foods: why salycitate is a signalling molecule if a cell has been attacked to other cells.
- Eat low Glyphosate foods : ( to be reviewed)
- Beware B3/B6 inhibiting foods : Nutrition-dependent GABA deficiencies in endocrine pancreas causes cancer, as shown for betel nut consumers and for diets de-activating vitamin B6 ( OA publishing )
Monday, 21 April 2014
Hair Lustre and Probiotics April Easter 2014
Greta post by Paul
You might be interested in this post https://www.facebook.com/TheSilverHydra/posts/10152383181385281?stream_ref=1
I thought that PLoS study (linked in that FB post) was fascinating. Check out figure one, the hair growth and hair quality is incredible. Have you researched L. reuteri much?
Frank Kurtis facebook page
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0053867
You might be interested in this post https://www.facebook.com/TheSilverHydra/posts/10152383181385281?stream_ref=1
I thought that PLoS study (linked in that FB post) was fascinating. Check out figure one, the hair growth and hair quality is incredible. Have you researched L. reuteri much?
Frank Kurtis facebook page
Food
for thought, in the past skin comorbidities and mental health disorders
seem to be highly correlated and benefits of probiotics (intestinal
bacteria) on the skin seem to use the same mediators as when they
benefit the brain.
Although very preliminary, some researchers are extending the whole 'gut-brain axis' thing to be 'gut-brain-skin axis' since they are all interrelated and skin can be used to visually assess (very roughly) the other organs status.
Some free reading:
http://www.ncbi.nlm.nih.gov/pubmed/23886975
http://www.ncbi.nlm.nih.gov/pubmed/21281494
And finally, a cool hypothetical study from PLoS about the whole 'glow of health' interrelating fertility and physical attraction via the gut. The supplement in question is lactobaciullus reuteri, and I'm looking into it currently:
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0053867
Basically what I'm trying to say is eat your fiber; it not only makes you pretty but probably makes you smarter.
L. reuteri is the prime agent testedAlthough very preliminary, some researchers are extending the whole 'gut-brain axis' thing to be 'gut-brain-skin axis' since they are all interrelated and skin can be used to visually assess (very roughly) the other organs status.
Some free reading:
http://www.ncbi.nlm.nih.gov/pubmed/23886975
http://www.ncbi.nlm.nih.gov/pubmed/21281494
And finally, a cool hypothetical study from PLoS about the whole 'glow of health' interrelating fertility and physical attraction via the gut. The supplement in question is lactobaciullus reuteri, and I'm looking into it currently:
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0053867
Basically what I'm trying to say is eat your fiber; it not only makes you pretty but probably makes you smarter.
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0053867
Abstract out of MIT
Radiant skin and hair are universally recognized as indications of good health. However, this ‘glow of health’ display remains poorly understood. We found that feeding of probiotic bacteria to aged mice induced integumentary changes mimicking peak health and reproductive fitness characteristic of much younger animals. Eating probiotic yogurt triggered epithelial follicular anagen-phase shift with sebocytogenesis resulting in thick lustrous fur due to a bacteria-triggered interleukin-10-dependent mechanism. Aged male animals eating probiotics exhibited increased subcuticular folliculogenesis, when compared with matched controls, yielding luxuriant fur only in probiotic-fed subjects. Female animals displayed probiotic-induced hyperacidity coinciding with shinier hair, a feature that also aligns with fertility in human females. Together these data provide insights into mammalian evolution and novel strategies for integumentary health.Hair washing - Dont forget- condition first, wash after, i wonder if this feeds bacteria near the follicle?
Lucy Colitis Easter April 2014
A Colitis and oral/ Tongue Bacteria Story:
Lucy,a 15 yo jack russell terrier has severe, almost life threatening , occasional bouts of colitis, preceded with mucus on stools.over a 2 day cycle. Broccoli at dinner is a favoured part of her diet. Can we learn from this preference for a green vegetable?
Enter last night this murine model paper- “Preventive and therapeutic effects of nitrite supplementation in experimental inflammatory bowel disease” http://www.sciencedirect.com/science/article/pii/S2213231713001006
Highlights
• Inorganic nitrate and nitrite alleviate DSS-induced colitis.
• Dietary nitrite has therapeutic effects in already established colonic inflammation.
• DSS-induced thinning of the colonic mucus layer is prevented by dietary nitrite.
• Nitrite promotes healing of colon epithelial cells.
Now the interesting part is that circulating nitrate is converted by bacteria on the tongue to nitrite! http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575935/
“The site of nitrate reduction to nitrite in humans is almost exclusively on the posterior third of the tongue, by nitrate reductase‐containing symbiotic bacteria, predominantly Veillonella species, as well as Actinomyces, Rothia and Staphylococcus epidermidis [b117,b118]. Whilst some conversion of nitrate to nitrite occurs on the ‘first pass’ of nitrate‐containing food over the surface of the tongue before it is initially swallowed, the majority of nitrate reduction to nitrite occurs over the subsequent few hours, via the entero‐salivary circulation [1], following concentration of nitrate in the salivary glands, and secretion in saliva, as described above [107,113,115,116].
So the experiment started last night- to lift the amount of nitrate in food and test the palatibility of foods; last night, first test – smoked salmon- eaten with relish. This morning, wilted lettuce with smoked salmon – eaten with relish. So we keep going with finding interesting sources of dietary nitrates.
As an aside, while there is strong interest in repairing the effect of episodic bouts of antibiotics on gut flora, I am increasingly interested in the prospects of continuous insults to flora, via ” innocuous” chloroamines in drinking water to oral bacteria ecology and the reaction in the stomach of amine and nitro compounds.
Now this little story gives a little encouragement to examine the life cycle of dietary recommendations for humans. An example is outlined in this abstract http://www.ncbi.nlm.nih.gov/pubmed/19439460
“Food sources of nitrates and nitrites: the physiologic context for potential health benefits”. The suggested intake is up to 550% greater than guidelines.
DSS Dextran Sodium Sulphate Colitis Mouse Model: Traps and Tricks DSS is a polysaccharide with various MW supplies. Different effects occur with different MW.
Oral bacteria thread , excellent
H Pyroli uses nickel in its enzymes , Stores it, and nickel can come from Stainless steel cutlery and pots
Sepiapterin ameliorates chemically induced murine colitis and azoxymethane-induced colon cancer
C60 forum
Lucy,a 15 yo jack russell terrier has severe, almost life threatening , occasional bouts of colitis, preceded with mucus on stools.over a 2 day cycle. Broccoli at dinner is a favoured part of her diet. Can we learn from this preference for a green vegetable?
Enter last night this murine model paper- “Preventive and therapeutic effects of nitrite supplementation in experimental inflammatory bowel disease” http://www.sciencedirect.com/science/article/pii/S2213231713001006
Highlights
• Inorganic nitrate and nitrite alleviate DSS-induced colitis.
• Dietary nitrite has therapeutic effects in already established colonic inflammation.
• DSS-induced thinning of the colonic mucus layer is prevented by dietary nitrite.
• Nitrite promotes healing of colon epithelial cells.
Now the interesting part is that circulating nitrate is converted by bacteria on the tongue to nitrite! http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3575935/
“The site of nitrate reduction to nitrite in humans is almost exclusively on the posterior third of the tongue, by nitrate reductase‐containing symbiotic bacteria, predominantly Veillonella species, as well as Actinomyces, Rothia and Staphylococcus epidermidis [b117,b118]. Whilst some conversion of nitrate to nitrite occurs on the ‘first pass’ of nitrate‐containing food over the surface of the tongue before it is initially swallowed, the majority of nitrate reduction to nitrite occurs over the subsequent few hours, via the entero‐salivary circulation [1], following concentration of nitrate in the salivary glands, and secretion in saliva, as described above [107,113,115,116].
So the experiment started last night- to lift the amount of nitrate in food and test the palatibility of foods; last night, first test – smoked salmon- eaten with relish. This morning, wilted lettuce with smoked salmon – eaten with relish. So we keep going with finding interesting sources of dietary nitrates.
As an aside, while there is strong interest in repairing the effect of episodic bouts of antibiotics on gut flora, I am increasingly interested in the prospects of continuous insults to flora, via ” innocuous” chloroamines in drinking water to oral bacteria ecology and the reaction in the stomach of amine and nitro compounds.
Now this little story gives a little encouragement to examine the life cycle of dietary recommendations for humans. An example is outlined in this abstract http://www.ncbi.nlm.nih.gov/pubmed/19439460
“Food sources of nitrates and nitrites: the physiologic context for potential health benefits”. The suggested intake is up to 550% greater than guidelines.
Background Notes for oral biome
DSS Dextran Sodium Sulphate Colitis Mouse Model: Traps and Tricks DSS is a polysaccharide with various MW supplies. Different effects occur with different MW.
Oral bacteria thread , excellent
H Pyroli uses nickel in its enzymes , Stores it, and nickel can come from Stainless steel cutlery and pots
Sepiapterin ameliorates chemically induced murine colitis and azoxymethane-induced colon cancer
C60 forum
Friday, 11 April 2014
easter 2014
bike safety
bike safety proviz
food of the prophet
kidney fibrosis gum arabica
fibre and goblet cells pdf
trader family isreali family
dropbox
heather gum arabica
duckweed gardening
Proviz jacket
Kickstarter back support
Kickstarter blue light belt
fx articles
indonesian boys
Isreali Boys
Armstrong is Daily CHart
bike safety proviz
food of the prophet
kidney fibrosis gum arabica
fibre and goblet cells pdf
trader family isreali family
dropbox
heather gum arabica
duckweed gardening
Proviz jacket
Kickstarter back support
Kickstarter blue light belt
fx articles
indonesian boys
Isreali Boys
Armstrong is Daily CHart
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Posts (Atom)
April 3rd, 2014 at 7:51 am “I read through this site: sulfite oxidase enzyme:”
Originally was
“I found the page below particularly helpful because it mentioned Molybdenum is a vital part of the sulfite oxidase enzyme”
And it looks like this other link completely disappeared:
http://www.learningtarget.com/nosulfites/>www.learningtarget.com
April 3rd, 2014 at 12:03 pm August, great example of using careful observation and personal science to diagnose and treat yourself – and I think it’s pretty obvious that traditional medicine would never have figured this out. And thanks for sharing, maybe this will help someone else who is having similar problems.
April 3rd, 2014 at 1:50 pm Thanks JM.
It looks like I need to correct my correction. The link is:
http://www.learningtarget.com/nosulfites/
April 3rd, 2014 at 2:52 pm Dear August,
Thank you for taking the time to write about your inspiring detective work! Its is extremely valuable to be able to mull over your process in approach; i am starting on a Lynch Syndrome path.
best
john
April 3rd, 2014 at 6:22 pm August:
I just checked my 23&me data. My results are the exactly the same as Red Ringlets and yours: SUOX rs10876864 AA, rs705703 CC, i5000977 AA, i5000976 AA . That would finally explain why I get such intense headaches when I drink red wine.
April 4th, 2014 at 1:48 pm Sorry. It appeared correctly in the visual editor.
April 6th, 2014 at 9:27 am I started supplementing with molybdenum after I did a hair minerals analysis test which showed very low levels of molybdenum. I felt better. 23andme said that I was a slow metabolizer of caffeine. Molybdenum is used in caffeine detoxification via xanthine oxidase. Supplementation helped reduce caffeine withdrawal symptoms the next day.
The farmer who I buy almost all of my beef from commented that my hair test was similar to his soil minerals test. A different local farmer commented that her soil minerals test showed a deficiency in molybdenum. When I go to the farmer’s market, I find that asking farmers if they do soil mineral tests and supplementation is a good indicator of whether their food will taste good. The best farmers test beyond ph, Ca, Mg, N, P, K to a plethora of micronutrients Mo, Se, Fe, Cu, Zn, B, Mn, Cr, Co, etc. Soil mineral deficiencies become mineral deficiencies in the plants and animals grown on that soil. People can’t go to nutritiondata.com, plug in their daily diet, and assume that their diet contains all the necessary minerals because the website says it should.
One of William Albrecht’s themes was that the soil quality in the South is compromised due to heat and precipitation leaching out the minerals from the soil. Maybe it is coincidence that the author is from the South. I don’t know.
Other minerals which were low on the test like lithium (5 mg/day) and magnesium (via MgCl foot baths), I also noticed a benefit from supplementing. But I haven’t noticed a benefit from supplementing selenium.
April 6th, 2014 at 9:33 am My markers are
SUOX 56398711 i5000976 AA
SUOX 56397916 i5000977 AA
SUOX 56391486 rs705703 CC
intergenic 56401085 rs10876864 AG
I haven’t noticed a reaction to sulfites or sulfur containing foods.
April 15th, 2014 at 10:41 am Hello, August,
Thanks for writing this article. I imagine you might be helping many people; perhaps you’ve helped me at least. If nothing else, it’s another hypothesis for me to test.
I believe I could have this issue with sulfites, so I’ve begun a low sulfur diet. I too have IBS that got slightly better on a low FODMAP diet, but by no means took care of it completely.
I’m wondering a couple things:
1. You say that you had normal BM’s after two weeks. Did that two week period include supplementing with molybdenum or was that on the low sulfite diet alone?
2. I have a number of symptoms that I think are related to the IBS such as insomnia and difficulty concentrating. Did you too have symptoms related to your IBS? If so, did they go away or show improvement in two weeks too?
Thanks!
April 18th, 2014 at 12:08 am Hi August
Thank you for taking the time to write down this post. It was really interesting, and I will try this out over the coming weeks. I will start today and take away MSM and instead put in some molyben.
The last entry from Louis was really interesting and I am very intressted in your comments on that, because that is a big thing even for me.
2. I have a number of symptoms that I think are related to the IBS such as insomnia and difficulty concentrating. Did you too have symptoms related to your IBS? If so, did they go away or show improvement in two weeks too?
Kindly
Anne